Authors: Dr Sav Zwickl and A/Prof Ada Cheung.
What are oestradiol implants?
An estradiol implant is a small, slow-release pellet containing the hormone oestradiol. Implants are inserted into the fatty tissue under the skin, preferably in the top of the buttock.
The Australian Informed Consent Standards of Care for Gender Affirming Hormone Therapy recommend a starting dose of 100mg every 6-12 months, and a maximum dose of 200mg every 6-12 months. In a recent survey, we asked trans people using oestradiol implants about the frequency of their implants, and the majority reported that their implant was replaced when their oestradiol blood concentrations fell below a certain level (57%), indicating the importance of regular blood tests. 15% of the people we asked, had their implant replaced 6 monthly, while 4% had it replaced every 9 months, and 8% yearly.
